Monday 26 November 2012

Myocardial Rupture

Myo·car·di·al
adj. 
Myo translates to muscle (Ancient Greek: Mus or Mys), while cardia/cardio translates to heart (Ancient Greek: Kardia)

A myocardial rupture is a laceration or the tearing of any part of the heart. It is a quite rare, and usually fatal complication of myocardial infarction (heart attacks).
It accounts for roughly 1/4th of all deaths caused (indirectly) by myocardial infarction.[1]


 Causes
- Myocardial infarction[1]
- Cardiac trauma
- Endocarditis (inflammation of the heart)[3]
- Cardiac tumors
- Infiltrative diseases of the heart[2][3]

Risk groups
- Women <70yo. Note that it affects a large number of women aged <70, whereas it kills a large number of women >70[4] 
- Increasing age[4]
- People with recent myocardial infarction[1][4]

Symptoms

The symptoms are achingly similar to the symptoms present in patients suffering myocardial infarction. Some patients may be relatively asymptomatic.
- Death, possibly.

- Cool, clammy skin
- Intense pain near the heart area
- Shortness of breath

- Heart failure
- Shock

[1] Shamshad, F., et all,  Fatal myocardial rupture after acute myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: The VALsartan In Acute myocardial iNfarcTion Trial (VALIANT), Febuary 24th, 2010, American Heart Journal, Volume 160, Issue 1, p145-151, July 2010
[2] Pai, R.K., et all, Giant periprosthetic vegetation associated with pseudoaneurysmal-like rupture, April 2006, European Heart Journal, Volume 27, Issue 8, p912
[3] Su, H.M., et all, Association between hypertension and  Primary Mitral Chordae Terdinae Rupture, 2006, American Journal of Hypertension, 19, p75-79
[4] Vedin, A., Rupture of the myocardium. Occurrence and risk factors., July 1985, British Heart Journal, 54(1), p11-16

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